Methandienone (danabol) is a most famous and widely used steroid in sports.
The structure of Methandienone contains a 17-alpha-methyl group. It is the alkylation of C17-alpha that makes the oral use of this anabolic steroid possible, with a very noticeable effect on the body (and a negative effect on the liver).
The half-life of Methandienone is 4.5-6 hours. The drug has moderate estrogenic effects, and its rate of conversion into a metabolite with more pronounced androgenic properties through the enzyme 5-alpha reductase is low. Methandienone’s benefits have made it popular among bodybuilders and athletes looking to increase muscle mass and strength.
It binds to SHBG worse than other steroids, therefore, even at high rates, the steroid remains in a free state.
The Manufacturer Company sought to create a steroid that has a lower androgen rate compared to testosterone, but retains the property of increasing muscle mass (anabolism). It did this by altering the basic chemical structure of testosterone in such a way that it changed its metabolism and location in the body. With the help of famous Dr. Ziegler, Ciba launched one of the “most effective oral anabolic steroids”. The drug was released in 1958 and is the most studied steroid after Testosterone.
EFFECTS:
Promotes rapid increase strength and muscle mass
Improves your recovery
Increase the level of glycogen
Increased appetite.
Methandienone improves your recovery and quickly adapts to stimuli, contributing not only to hypertrophy, but also hyperplasia (enlargement of certain organs). Along with this there is an excellent increase in muscle nitrogen retention, providing an excellent anabolic environment.
Methandienone reduces the level of glycogenolysis, that is, the breakdown of glycogen. Glycogen, which is one of the factors responsible for muscle volume, for the retention of water in the muscle tissue, as well as for the supply of energy to muscles, of course, with its higher concentrations in the muscle environment, we have obtained more satisfactory results.
Methandienone is also an anabolic known to increase strength and fluid retention potential, helping to prevent joint damage that can be caused by increased strength.
Methandienone cycles usually produce results in a very short time, which is also an advantage. For example, in 4 weeks of using Methandienone, an increase of 4-6 kg is achieved. It is because of this characteristic of rapid weight gain that Methandienone can be used at the beginning of any cycle.
SIDE EFFECTS:
Increased aromatization risk
The rise in blood pressure
An increase in cholesterol levels
Androgenic side effects are possible: hair loss on the scalp, acne, suppression of the production of its own testosterone, etc.
Toxicity to the liver – manifested through alpha-17-alkylation
Myocardial hypertrophy – especially at high doses.
DOSAGE:
Methandienone is usually used initially in a cycle, as “start up.” Average dosages for an initial cycle of Methandienone are 50-60 mg per day, but for more advanced athletes, doses of 100-150 mg per day are relatively common.
Among the side effects, aromatization can be highlighted, which means that it can cause a significant increase in the level of female hormones during its use as well as after its use.
Methandienone significantly increases dopamine levels, which has a positive effect on mood, motivation and libido.
Higher dosages of the drug (100 mg and above) make sense only during solo use of this steroid, as a rule, when it is combined with others steroids, its dosage does not exceed 50 mg per day, even in experienced athletes.
Half-life: 6-8 hours.
Duration of action: 12-15 hours.
Frequency of intake: 3 times a day.
Hepatotoxic rate: Moderate.
Converts to DHT: Not.
Detection time: More than 6 weeks*
*- approximate drug concentrations at various dosages
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